| TCI产品编码 : | T0459 | ||||||||||||||
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| 库存情况 : |
2012年02月09号上午06点的情况 *2012年4月前，中国库存将暂时显示上海仓库和天津仓库的库存总和。 |
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| 纯度 / 分析方法 : | >95.0%(T) | ||||||||||||||
| 保存温度 : | Refrigerator | ||||||||||||||
| 分子式 / 分子量 : | C15H23ClO2S=302.86 | ||||||||||||||
| CAS编码 : | 6553-96-4 | ||||||||||||||
| 相关CAS编码 : | |||||||||||||||
| MDL编码 : | MFCD00007433 | ||||||||||||||
| 监管条件代码 : | |||||||||||||||
| 国内危险化学品编码 : | |||||||||||||||
| mp : | 96 °C |
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Efficient synthesis of N2-dimethylaminomethylene-2’-O-methylguanosine Typical procedure (protection of the O6-position of guanosine): To a suspension of 3’,5’-O-di-tert-butylsilanediylguanosine (2.12 g) in dry CH2Cl2 are added DMAP (0.122 g), Et3N (4.18 mL), and 2,4,6-triisopropylbenzenesulfonyl chloride (4.68 g) under argon. The reaction mixture is stirred at room temperature for 3 h and then the solvent is removed under reduced pressure. The residue is dissolved in ethyl acetate and the solution is washed with saturated NaHCO3 solution and brine, and dried over Na2SO4. After filtration, the solvent is evaporated in vacuo. The residue is purified by column chromatography (eluent: 50-60 % CHCl3 in hexane) to give the O6-protected guanosine as a colorless foam (3.34 g, 97%). |
| F & F : | 6, 622 |
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| UN编号 : | 3261 |
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| Class : | 8 |
| PG : | III |
| TCI产品学术记录 : | |
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| 相关分类 : |
Synthetic Organic Chemistry
Condensation & Active Esterification
Biochemistry Nucleosides, Nucleotides & Related Reagents Protecting Agents, Phosphorylating Agents & Condensing Agents Protecting Agents for Hydroxyl and Amino Groups Biochemistry Nucleosides, Nucleotides & Related Reagents Protecting Agents, Phosphorylating Agents & Condensing Agents Condensing Agents (DNA / RNA Synthesis) Synthetic Organic Chemistry Sulfur Compounds (for Synthesis) Sulfonic Acid Derivatives Sulfonic Acid Derivatives (Others) |