| TCI产品编码 : | B1045 | ||||||||||||||
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| 库存情况 : |
2012年02月08号上午06点的情况 *2012年4月前，中国库存将暂时显示上海仓库和天津仓库的库存总和。 |
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| 纯度 / 分析方法 : | >98.0%(T) | ||||||||||||||
| 保存温度 : | |||||||||||||||
| 分子式 / 分子量 : | C16H24Cl2Rh2=493.08 | ||||||||||||||
| CAS编码 : | 12092-47-6 | ||||||||||||||
| 相关CAS编码 : | |||||||||||||||
| MDL编码 : | MFCD00012415 | ||||||||||||||
| 监管条件代码 : | |||||||||||||||
| 国内危险化学品编码 : | |||||||||||||||
Rhodium-Catalyzed Cross-coupling of Organoboron Compounds with Vinyl Acetate Typical procedure: Under nitrogen atmosphere, a mixture of an arylboron compounds (0.50 mmol), [RhCl(cod)]2 (6.2 mg, 13 μmol), DPPB (11.7 mg, 28 μmol), and K3PO4 (320 mg, 1.5 mmol) is diluted with toluene (2.0 mL). Alkenyl acetate (1.1 or 2.5 mmol) and tert-amyl alcohol (0.55-1.5 mmol) are added into the resulting suspension at room temperature. The mixture is stirred at 100℃ for 24 h and then diluted with hexane (2.0 mL) or EtOAc (2.0 mL). After the filtration through a Celite pad, solvent is removed from the filtrate under reduced pressure. The residue is purified with a flash column chromatography (EtOAc-hexane) to give the desired product. 1,2-Addition of Chiral Secondary and Tertiary Alkyl Trifluoroborate Typical procedure: A dry Schlenk tube flask is charged with the potassium trifluoroborate salt (0.45 mmol), [RhCl(cod)]2 (2.5 mol%, 3.6 mg) and the aldehyde (0.3 mmol). After cycles of vacuum and nitrogen (3 cycles), deoxygenated 1,4-dioxane (1.4 mL) and deoxygenated H2O (240 μL) are added. The reaction mixture is stirred at 60-100ºC and the progress of the reaction is checked by TLC. The mixture is cooled to room temperature, saturated NH4Cl solution is added, and then the mixture is extracted with EtOAc. The combined organic layers are dried over MgSO4. Concentration and purification through silica gel column chromatography gives the products. |
| 相关分类 : |
Structure of Chemicals
Classes of Metal Compounds
Transition Metal Compounds
Rh (Rhodium) Compounds
Synthetic Organic Chemistry Catalysts for Organic Synthesis Homogeneous Catalysts Metal Complexes Synthetic Organic Chemistry Catalysts for Organic Synthesis Homogeneous Catalysts Rhodium |
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